EW AND GENETICS ( BIO WEAPON-6)
ENTOMOLOGICAL
WARFARE
is a type of biological warfare that uses insects to attack the enemy. The concept has existed for centuries and research and development have continued into the modern era. EW has been used in battle by Japan and several other nations have developed and been accused of using an entomological warfare program. EW may employ insects in a direct attack or as vectors to deliver a biological agent, such as plague. Essentially, EW exists in three varieties. One type of EW involves infecting insects with a pathogen and then dispersing the insects over target areas.[] The insects then act as a vector, infecting any person or animal they might bite. Another type of EW is a direct insect attack against crops; the insect may not be infected with any pathogen but instead represents a threat to agriculture. The final method uses uninfected insects, such as bees or wasps, to directly attack the enemy.
GENETICS
Theoretically, novel approaches in biotechnology, such as synthetic biology could be used in the future to design novel types of biological warfare agents.
Would demonstrate how to render a vaccine ineffective;
Would confer resistance to therapeutically useful antibiotics or antiviral agents;
Would enhance the virulence of a pathogen or render a nonpathogen virulent;
Would increase the transmissibility of a pathogen;
Would alter the host range of a pathogen;
Would enable the evasion of diagnostic/detection tools;
Would enable the weaponization of a biological agent or toxin.
Most of the biosecurity concerns in synthetic biology are focused on the role of DNA synthesis and the risk of producing genetic material of lethal viruses (e.g. 1918 Spanish flu, polio) in the lab.[] Recently, the CRISPR/Cas system has emerged as a promising technique for gene editing. It was hailed by The Washington Post as "the most important innovation in the synthetic biology space in nearly 30 years."[] While other methods take months or years to edit gene sequences, CRISPR speeds that time up to weeks.[3] Due to its ease of use and accessibility, it has raised a number of ethical concerns, especially surrounding its use in the biohacking space.
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